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The all2 gene is required for the induction of the purine deamination pathway in Schizosaccharomyces pombe
- Source :
- Journal of general microbiology. 131(3)
- Publication Year :
- 1985
-
Abstract
- SUMMARY: Five mutants were isolated at the all2 gene on the basis of their inability to utilize hypoxanthine as a sole source of nitrogen. These mutants failed to utilize the purines adenine, hypoxanthine, xanthine, uric acid, allantoin and allantoic acid, although they could utilize urea and ammonium. The all2 mutants appeared to be defective in purine induction of uricase, allantoinase, allantoicase and ureidoglycollase activities but retained wild-type activity of the constitutively synthesized urease. The all2 mutations were recessive.
- Subjects :
- Allantoic acid
Purine
Urate Oxidase
Genes, Fungal
Allantoinase
Lyases
Biology
Microbiology
Ureohydrolases
Amidohydrolases
chemistry.chemical_compound
Ascomycota
Schizosaccharomyces
Allantoicase
Purine metabolism
Hypoxanthine
Xanthine
Urease
chemistry
Biochemistry
Deamination
Purines
Enzyme Induction
Amidine-Lyases
Mutation
Uric acid
Subjects
Details
- ISSN :
- 00221287
- Volume :
- 131
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Journal of general microbiology
- Accession number :
- edsair.doi.dedup.....6b549e58d06fe6d7217607c80dc8dbaa