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Next generation metronomic chemotherapy—report from the Fifth Biennial International Metronomic and Anti-angiogenic Therapy Meeting, 6–8 May 2016, Mumbai
- Source :
- Ecancermedicalscience, Ecancermedicalscience, 2016, 10, ⟨10.3332/ecancer.2016.689⟩, Ecancermedicalscience, ecancer Global Foundation, 2016, 10, ⟨10.3332/ecancer.2016.689⟩, ecancermedicalscience
- Publication Year :
- 2016
- Publisher :
- Ecancer Global Foundation, 2016.
-
Abstract
- International audience; The 5th Biennial Metronomic and Anti-angiogenic Therapy Meeting was held on 6th – 8th May in the Indian city of Mumbai. The meeting brought together a wide range of clinicians and researchers interested in metronomic chemotherapy, anti-angiogenics, drug repurposing and combinations thereof. Clinical experiences, including many from India, were reported and discussed in three symposia covering breast cancer, head and neck cancers and paediatrics. On the pre-clinical side research into putative mechanisms of action, and the interactions between low dose metronomic chemotherapy and angiogenesis and immune responses, were discussed in a number of presentations. Drug repurposing was discussed both in terms of clinical results, particularly with respect to angiosarcoma and high-risk neuroblastoma, and in pre-clinical settings, particularly the potential for peri-operative interventions. However, it was clear that there remain a number of key areas of challenge, particularly in terms of definitions, perceptions in the wider oncological community, mechanisms of action and pre- dictive biomarkers. While the potential for metronomics and drug repurposing in low and middle income countries remains a key theme, it is clear that there is also considerable potential for clinically relevant improvements in patient outcomes even in high income economies.
- Subjects :
- 0301 basic medicine
Cancer Research
medicine.medical_specialty
Psychological intervention
[SDV.CAN]Life Sciences [q-bio]/Cancer
Pharmacology
LMIC
03 medical and health sciences
0302 clinical medicine
Breast cancer
[SDV.CAN] Life Sciences [q-bio]/Cancer
metronomic chemotherapy
medicine
cancer
In patient
Intensive care medicine
Head and neck
drug repurposing
business.industry
Anti angiogenic
Cancer
Conference Report
anti-angiogenics
medicine.disease
Metronomic Chemotherapy
3. Good health
Drug repositioning
030104 developmental biology
Oncology
030220 oncology & carcinogenesis
business
Subjects
Details
- ISSN :
- 17546605
- Volume :
- 10
- Database :
- OpenAIRE
- Journal :
- ecancermedicalscience
- Accession number :
- edsair.doi.dedup.....6b188d831110ed437dc595eff18d77d1