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Wearable Sensors in Huntington Disease: A Pilot Study
- Source :
- Journal of Huntington's Disease. 5:199-206
- Publication Year :
- 2016
- Publisher :
- IOS Press, 2016.
-
Abstract
- Background: The Unified Huntington’s Disease Rating Scale (UHDRS) is the principal means of assessing motor impairment in Huntington disease but is subjective and generally limited to in-clinic assessments. Objective: To evaluate the feasibility and ability of wearable sensors to measure motor impairment in individuals with Huntington disease in the clinic and at home. Methods: Participants with Huntington disease and controls were asked to wear five accelerometer-based sensors attached to the chest and each limb for standardized, in-clinic assessments and for one day at home. A secondchest sensor was worn for six additional days at home. Gait measures were compared between controls, participants with Huntington disease, and participants with Huntington disease grouped by UHDRS total motor score using Cohen’s d values. Results: Fifteen individuals with Huntington disease and five controls completed the study. Sensor data were successfully captured from 18 of the 20 participants at home. In the clinic, the standard deviation of step time (timebetween consecutive steps) was increased in Huntington disease (p
- Subjects :
- Adult
Male
0301 basic medicine
congenital, hereditary, and neonatal diseases and abnormalities
medicine.medical_specialty
Movement
Wearable computer
Pilot Projects
Disease
03 medical and health sciences
Cellular and Molecular Neuroscience
0302 clinical medicine
Physical medicine and rehabilitation
Huntington's disease
Rating scale
Accelerometry
mental disorders
medicine
Humans
Exercise
Gait
Motor score
Aged
Motor impairment
Chorea
Middle Aged
medicine.disease
Huntington Disease
030104 developmental biology
Physical therapy
Female
Neurology (clinical)
medicine.symptom
Psychology
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 18796400 and 18796397
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Journal of Huntington's Disease
- Accession number :
- edsair.doi.dedup.....6b02b842b47128db05a06edbdced0883