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Cough augmentation in amyotrophic lateral sclerosis
- Source :
- Neurology. 61(9)
- Publication Year :
- 2003
-
Abstract
- Cough flows and pressures were measured during cough augmentation in healthy subjects and patients with bulbar and nonbulbar amyotrophic lateral sclerosis. Manual assistance increased flow 11% in bulbar (p < 0.01) and 13% in nonbulbar (p < 0.001) patients. Mechanical insufflation-exsufflation increased flow 17% in healthy subjects (p < 0.05), 26% (p < 0.001) in bulbar, and 28% (p < 0.001) in nonbulbar patients. The greatest improvements were in patients with the weakest coughs. Patient group and level of weakness influenced the effect of augmentation.
- Subjects :
- Male
Weakness
medicine.medical_specialty
Ventilators, Negative-Pressure
Peak Expiratory Flow Rate
Central nervous system disease
Reference Values
Reflex
medicine
Humans
In patient
Amyotrophic lateral sclerosis
Patient group
Inhalation
business.industry
Amyotrophic Lateral Sclerosis
Healthy subjects
Exhalation
medicine.disease
Respiration, Artificial
Surgery
Treatment Outcome
Cough
Anesthesia
Female
Neurology (clinical)
medicine.symptom
business
Respiratory Insufficiency
Subjects
Details
- ISSN :
- 1526632X
- Volume :
- 61
- Issue :
- 9
- Database :
- OpenAIRE
- Journal :
- Neurology
- Accession number :
- edsair.doi.dedup.....6a8584ed48fd40acd993b8822963f9c3