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Human Cystic Echinococcosis: Old Problems and New Perspectives

Authors :
Elena Ortona
Alessandra Siracusano
Antonella Teggi
Source :
Interdisciplinary Perspectives on Infectious Diseases, Vol 2009 (2009), Interdisciplinary Perspectives on Infectious Diseases
Publication Year :
2009
Publisher :
Hindawi Limited, 2009.

Abstract

Cystic echinococcosis (CE) is a widespread chronic endemic helminthic disease caused by infection with metacestodes of the tapewormEchinococcus granulosus. CE affects humans and has a worldwide prevalence of approximately six million. In this review, we discuss current findings in diagnosis and clinical management of CE and new concepts relating toE. granulosusmolecules that directly modulate the host immune responses favouring a strong anti-inflammatory response and perpetuating parasite survival in the host. New insights into the molecular biology ofE. granulosuswill improve considerably our knowledge of the disease and will provide new potential therapeutic applications to treat or prevent inflammatory immune-mediated disease.

Details

Language :
English
ISSN :
16877098
Volume :
2009
Database :
OpenAIRE
Journal :
Interdisciplinary Perspectives on Infectious Diseases
Accession number :
edsair.doi.dedup.....69e0c31df7d7ec83a99d88f63a23b254