Posttransplant lymphoproliferative disorders in small bowel allograft recipients

We have previously estimated a 20% frequency of Epstein–Barr virus (EBV) related post-transplant lymphoproliferative disorders (PTLD) in small bowel allograft recipients. 1 The present study compares rates of PTLD among pediatric and adult recipients of isolated or composite small bowel allografts. We also report PTLD frequency before and after the institution of quantitative EBV monitoring and the use of ancillary donor bone marrow infusion to facilitate microchimerism, both of which began in mid-1994.