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Supplementary Table 1 and Supplementary Figures 1 through 6 from CSN1 Somatic Mutations in Penile Squamous Cell Carcinoma

Authors :
John D. Kelly
Asif Muneer
Tyson V. Sharp
Tim Fenton
Stephan Beck
Tom Powles
Gareth A. Wilson
Charles Jameson
Alex Freeman
Simon Rodney
Wei Shen Tan
Peter R. Malone
Raj Nigam
Muhammad Saqib
Manit Arya
Kunal Shah
Patricia de Winter
Ankur Chakravarthy
Daniel C. Worth
Andrew Feber
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Supplementary Table 1. A)Patient details for Fresh Frozen test cohort, B) Patient details for validation cohort. Supplementary Figure 1. APOBEC mutation fraction of across multiple cancer types. Supplementary Figure 2. DNA methylation. Supplementary Figure 3. Candidate PeCa driver mutations. Supplementary Figure 4. Schematic of FAT1 is shown with locations of mutations and ethylation states of PeCa and normal penile tissue across the canonical FAT1 gene. Supplementary Figure 5. A) Example plot of Copy Number Alterations (CNA) in penile cancers, 450K methylation profiles for penile cancer and normal squamous epithelium, and output from GISTIC showing the frequency and significance of CNAs.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....699ead6d2c936e199f3310310b0271a9