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Breastfeeding by chikungunya virus-infected dams confers resistance to challenge in the offspring
- Source :
- Translational Research. 255:109-118
- Publication Year :
- 2023
- Publisher :
- Elsevier BV, 2023.
-
Abstract
- Vertical transmission of Chikungunya virus (CHIKV) has been reported in humans, but the transmission routes have not been completely understood, and experimental animal models are needed to enable detailed investigation of the transmission and pathogenesis of congenital infections. The intertwining of immune response and virus components at the gestation/breastfeeding interfaces between mother and fetus/newborn may have effects during the offspring development. An experimental model of CHIKV was established by infecting pregnant BALB/c female mice that enabled confirmation that dams inoculated up to the 10
Details
- ISSN :
- 19315244
- Volume :
- 255
- Database :
- OpenAIRE
- Journal :
- Translational Research
- Accession number :
- edsair.doi.dedup.....698f706066c55b8527b0fc6f2a56ceb0
- Full Text :
- https://doi.org/10.1016/j.trsl.2022.12.001