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Catalytic cycloaddition of 2-hydroxy ketones with 1,1-dicyanoalkenes
- Source :
- Organicbiomolecular chemistry. 14(5)
- Publication Year :
- 2016
-
Abstract
- A tin-catalyzed reaction of α-hydroxy ketones with 1,1-dicyanoalkenes produced 2-amino-4,5-dihydrofuran-3-nitriles. In the catalytic reaction, tin enolates were generated from α-hydroxy ketones as active catalytic species. The highly basic ability of the Sn-O bonds played an important role in the reactions. This tin-catalyzed reaction was highly atom-economical and required no other metal reagents.
- Subjects :
- 010405 organic chemistry
Chemistry
Organic Chemistry
chemistry.chemical_element
equipment and supplies
010402 general chemistry
01 natural sciences
Biochemistry
Cycloaddition
0104 chemical sciences
Catalysis
Metal
Reagent
visual_art
visual_art.visual_art_medium
Organic chemistry
Physical and Theoretical Chemistry
Tin
Subjects
Details
- ISSN :
- 14770539
- Volume :
- 14
- Issue :
- 5
- Database :
- OpenAIRE
- Journal :
- Organicbiomolecular chemistry
- Accession number :
- edsair.doi.dedup.....68db5ee99ecd8e0944462178908f6a50