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Oxygen Uptake Attenuation at Ventilatory Threshold in Men With Coronary Artery Disease
- Source :
- Journal of cardiopulmonary rehabilitation and prevention. 36(4)
- Publication Year :
- 2016
-
Abstract
- Purpose Maximal oxygen uptake ((Equation is included in full-text article.)O2) and ventilatory threshold (VT) are widely used to assess cardiorespiratory fitness in healthy people, as well as in patients with various clinical conditions. The aim of this study was to determine whether an attenuation of (Equation is included in full-text article.)O2 occurs above the VT in patients with stable coronary artery disease. Methods A total of 33 male patients participating in an outpatient cardiac rehabilitation/secondary prevention program underwent maximal incremental cycle ergometry at increasing pedaling cadences up to the limit of tolerance. Ventilatory gas-exchange variables were measured breath by breath while work rate was recorded continuously. Ventilatory threshold was determined by a dual linear regression model (V-slope analysis). Results Four patients were excluded from the analysis because they were unable to pedal at the increasing cadences required by the protocol. The remaining 29 patients successfully completed the test without complications or evidence of significant ST segment depression. The slope of the (Equation is included in full-text article.)O2/work rate relationship above the VT decreased significantly (-44.6% on average) in 23 of the 26 patients in which VT was able to be determined. (Equation is included in full-text article.)O2 at the start of (Equation is included in full-text article.)O2 attenuation ((Equation is included in full-text article.)O2att) and at VT were highly correlated and in strong agreement (1637 ± 451 mL/min vs 1650 ± 473 mL/min, r = 0.96, P Conclusions (Equation is included in full-text article.)O2att does occur and coincides with the VT in the majority of patients tested with stable coronary artery disease.
- Subjects :
- Pulmonary and Respiratory Medicine
Male
medicine.medical_specialty
Myocardial ischemia
Cardiopulmonary exercise testing
Oxygen uptake
Work rate
Rehabilitation
Cardiology and Cardiovascular Medicine
Physical Exertion
Coronary Artery Disease
030204 cardiovascular system & hematology
NO
Coronary artery disease
03 medical and health sciences
Electrocardiography
0302 clinical medicine
Oxygen Consumption
Internal medicine
Linear regression
medicine
ST segment
Humans
Aged
Exercise Tolerance
medicine.diagnostic_test
business.industry
Pulmonary Gas Exchange
VO2 max
Cardiorespiratory fitness
030229 sport sciences
Middle Aged
medicine.disease
Surgery
Cardiology
Exercise Test
business
Ventilatory threshold
Pulmonary Ventilation
Subjects
Details
- ISSN :
- 1932751X
- Volume :
- 36
- Issue :
- 4
- Database :
- OpenAIRE
- Journal :
- Journal of cardiopulmonary rehabilitation and prevention
- Accession number :
- edsair.doi.dedup.....68d21633b148c5c7a46fa4b89a496663