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Stabilization of microtubules by encapsulation of the GFP using a Tau-derived peptide
- Source :
- Inaba Hiroshi, Yamamoto Takahisa, Iwasaki Takashi, et al. Stabilization of microtubules by encapsulation of the GFP using a Tau-derived peptide. CHEMICAL COMMUNICATIONS. 2019. 55(62). 9072-9075. doi:10.1039/c9cc04345d
- Publication Year :
- 2019
- Publisher :
- Royal Society of Chemistry, 2019.
-
Abstract
- We constructed GFP-encapsulated microtubules (MTs) using Tauderived peptide which binds to their interior. The encapsulation of GFP dramatically increased the rigidity of MTs, resulting in their enhanced velocity on a kinesin-coated substrate. Moreover, the GFP-encapsulated MTs were significantly more stable compared to normal MTs.
- Subjects :
- Models, Molecular
Surface Properties
Green Fluorescent Proteins
tau Proteins
Peptide
macromolecular substances
010402 general chemistry
Microtubules
01 natural sciences
Catalysis
Green fluorescent protein
Rigidity (electromagnetism)
Microtubule
Materials Chemistry
Particle Size
chemistry.chemical_classification
urogenital system
010405 organic chemistry
Chemistry
fungi
Metals and Alloys
General Chemistry
0104 chemical sciences
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
Ceramics and Composites
Biophysics
Peptides
Subjects
Details
- Language :
- English
- ISSN :
- 13597345
- Volume :
- 55
- Issue :
- 62
- Database :
- OpenAIRE
- Journal :
- CHEMICAL COMMUNICATIONS
- Accession number :
- edsair.doi.dedup.....68bd9b4ea3debf20c09577f5f5c83348