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Rabies vaccinations: are abbreviated intradermal schedules the future?

Authors :
Abraham Goorhuis
Tjalling Leenstra
Rosanne W. Wieten
M. van Vugt
Martin P. Grobusch
Cornelis Stijnis
P. P. A. M. van Thiel
Infectious diseases
Amsterdam institute for Infection and Immunity
Amsterdam Public Health
Graduate School
Source :
Clinical infectious diseases, 56(3), 414-419. Oxford University Press
Publication Year :
2013

Abstract

Rabies is a deadly disease, and current preexposure vaccination schedules are lengthy and expensive. We identified nine studies investigating abbreviated schedules. Although initial responses were lower, accelerated adequate immune responses were elicited after booster vaccinations. Lower-dose (and therefore cheaper) vaccination schedules may constitute a valid alternative to current vaccination schedules.

Details

Language :
English
ISSN :
10584838
Volume :
56
Issue :
3
Database :
OpenAIRE
Journal :
Clinical infectious diseases
Accession number :
edsair.doi.dedup.....68b1cdb7d550468497bac903495fc64a
Full Text :
https://doi.org/10.1093/cid/cis853