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Supplementary Tables S1-S4 from Dual Targeting of CDK4 and ARK5 Using a Novel Kinase Inhibitor ON123300 Exerts Potent Anticancer Activity against Multiple Myeloma

Authors :
Samir Parekh
Sundar Jagannath
E. Premkumar Reddy
Weijia Zhang
M.V. Ramana Reddy
Joshua Brody
Ajai Chari
Hearn Jay Cho
Sai Krishna Athaluri Divakar
Zewei Jiang
Violetta V. Leshchenko
Pei-Yu Kuo
Deepak Perumal
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

Kinase Inhibition Profile of ON123300 and PD0332991 (S1); Top 10 significantly enriched pathways for the 894 differentially regulated genes from NCI-H929 siRNA RNA sequencing analysis (S2); Top 10 significantly enriched pathways for the 180 differentially regulated genes between ON123300 and resistant cell lines (S3); Top 10 significantly downregulated pathways for the 180 differentially regulated genes between ON123300 and resistant cell lines (S4).

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....68af6be06c4d5e0e7e2c7cec95da01f2