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Dietary inulin intake and age can significantly affect intestinal absorption of calcium and magnesium in rats : A stable isotope approach
- Source :
- Nutrition Journal (4), 8 p.. (2005), Nutrition Journal, Nutrition Journal, BioMed Central, 2005, 4, 8 p. ⟨10.1186/1475-2891-4-29⟩, Nutrition Journal, Vol 4, Iss 1, p 29 (2005)
- Publication Year :
- 2005
-
Abstract
- Background previous studies have shown that non-digestible inulin-type fructan intake can increase intestinal mineral absorption in both humans and animals. However, this stimulatory effect on intestinal absorption may depend on experimental conditions such as duration of fermentable fiber intake, mineral diet levels and animals' physiological status, in particular their age. Objectives the aim of this study was to determine the effect of inulin intake on Ca and Mg absorption in rats at different age stages. Methods eighty male Wistar rats of four different ages (2, 5, 10 and 20 months) were randomized into either a control group or a group receiving 3.75% inulin in their diet for 4 days and then 7.5% inulin for three weeks. The animals were fed fresh food and water ad libitum for the duration of the experiment. Intestinal absorption of Ca and Mg was determined by fecal monitoring using stable isotopic tracers. Ca and Mg status was also assessed. Results absorption of Ca and Mg was significantly lower in the aged rats (10 and 20 mo) than in the young and adult rat groups. As expected, inulin intake increased Ca and Mg absorption in all four rat groups. However, inulin had a numerically greater effect on Ca absorption in aged rats than in younger rats whereas its effect on Mg absorption remained similar across all four rat age groups. Conclusion the extent of the stimulatory effect of inulin on absorption of Ca may differ according to animal ages. Further studies are required to explore this effect over longer inulin intake periods, and to confirm these results in humans.
- Subjects :
- Male
Aging
030309 nutrition & dietetics
[SDV]Life Sciences [q-bio]
aliment
Medicine (miscellaneous)
magnesium
Weight Gain
Intestinal absorption
isotope stable
Eating
Feces
Cecum
chemistry.chemical_compound
0302 clinical medicine
Isotopes
absorption de substances nutritives
stable isotope
fermentation
lcsh:RC620-627
2. Zero hunger
0303 health sciences
Nutrition and Dietetics
intestinal absorption
Inulin
âge
lcsh:Nutritional diseases. Deficiency diseases
medicine.anatomical_structure
medicine.symptom
lcsh:Nutrition. Foods and food supply
Calcium Isotopes
medicine.medical_specialty
oligoélément
Nutritional Status
chemistry.chemical_element
lcsh:TX341-641
030209 endocrinology & metabolism
Absorption (skin)
Calcium
Isotopes of calcium
03 medical and health sciences
Internal medicine
medicine
Animals
Mineral absorption
Rats, Wistar
magnésium
status
calcium
inuline
business.industry
Research
Diet
Rats
Calcium, Dietary
Endocrinology
age
chemistry
RAT
business
Weight gain
Subjects
Details
- Language :
- English
- ISSN :
- 14752891
- Database :
- OpenAIRE
- Journal :
- Nutrition Journal (4), 8 p.. (2005), Nutrition Journal, Nutrition Journal, BioMed Central, 2005, 4, 8 p. ⟨10.1186/1475-2891-4-29⟩, Nutrition Journal, Vol 4, Iss 1, p 29 (2005)
- Accession number :
- edsair.doi.dedup.....68999b51eec9e5f0829412dfc0973fe7