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Feasibility of collection and analysis of microbiome data in a longitudinal randomized trial of community gardening
- Source :
- Future Microbiol
- Publication Year :
- 2020
- Publisher :
- Future Medicine Ltd, 2020.
-
Abstract
- Aim: We explored the feasibility of collecting and analyzing human microbiome data in a longitudinal randomized controlled trial of community gardening. Methods & materials: Participants were randomly assigned to gardening (N = 8) or control (N = 8). Participants provided stool, mouth, hand and forehead microbiome samples at six timepoints. Analyses combined mixed models with Qiita output. Results: Participant satisfaction was high, with 75% of participants completing evaluations. While no microbial effects were statistically significant due to small sample size, the analysis pipeline utility was tested. Conclusion: Longitudinal collection and analysis of microbiome data in a community gardening randomized controlled trial is feasible. The analysis pipeline will be useful in larger studies for assessment of the pathway between microbiota, gardening and health outcomes. This study was funded by the University of Colorado Boulder Population Center (CUPC, J Litt, PI), through the National Institute of Child Health & Human Development of the NIH under award number P2CHD066613-06 and the Center for Microbiome Innovation at the University of California San Diego. We also received supplemental funding through the Clinical & Translational Research Center (CTRC) to cover all laboratory costs (J Litt, PI). M Gascon received a fellowship from the Societat Econòmica Barcelonesa d'Amics del País (SEBAP) in 2018, Barcelona (Catalonia), for her research stay at the University of Colorado to conduct the statistical analysis for this work. DH Glueck was supported, in part, by R01GM121-81 and R25 GM111901
- Subjects :
- Microbiology (medical)
Gerontology
Adult
Male
medicine.medical_specialty
Health Promotion
Health outcomes
Microbiology
law.invention
Feces
Young Adult
Randomized controlled trial
law
Residence Characteristics
medicine
Humans
Microbiome
Forehead
Longitudinal Studies
Microbiologia -- Aspectes ambientals
Mouth
Bacteria
business.industry
Public health
Microbiota
Human microbiome
Small sample
Gardening
Middle Aged
Salut pública
Jardineria
Feasibility Studies
Female
Community gardening
business
Research Article
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Future Microbiol
- Accession number :
- edsair.doi.dedup.....688bfa6f204268f4d113457b2c4da1ae