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Change in testosterone concentrations over time is a better predictor than the actual concentrations for symptoms of late onset hypogonadism
- Source :
- The Aging Male. 14:249-256
- Publication Year :
- 2011
- Publisher :
- Informa UK Limited, 2011.
-
Abstract
- Background. Symptoms of late-onset hypogonadism (LOH) and concentrations of testosterone (T) and bioavailable testosterone (BT) were studied in relation to the data from the same men 5 years earlier. less thanbrgreater than less thanbrgreater thanMethods. In 2008, 282 men, aged 60-82 years, answered a questionnaire regarding demographic data, medical history, different symptoms of LOH and the 10 questions from the Androgen Decline in Aging Males (ADAM)-questionnaire. Blood samples were analysed for concentrations of T and calculations were made for BT. less thanbrgreater than less thanbrgreater thanResults. A total of 87.2% of the questionnaires were returned and analysed, and 75.2% of the responders gave blood samples. The oldest third of the men were most affected by LOH symptoms (p andlt; 0.05). Both T and BT concentrations decreased during the 5 years (p andlt; 0.05) but only the symptom less strong erections changed significantly (p andlt; 0.05). Men reporting one of the four specific symptoms from the ADAM-questionnaire for the first time in 2008 had a higher loss of T and BT than men who had unchanged or fewer symptoms than that reported in 2003. less thanbrgreater than less thanbrgreater thanConclusions. The magnitude of the decrease in concentrations is a better predictor of LOH than are the actual concentrations of T and BT. A combination of symptoms predicts LOH better than any single symptom. Funding Agencies|Swedish Medical Research Council|K2000-72X-12651-04B
- Subjects :
- Male
Aging
Medicin och hälsovetenskap
medicine.medical_specialty
medicine.drug_class
andrology
Late onset
Demographic data
Medical and Health Sciences
climacteric
Surveys and Questionnaires
Internal medicine
medicine
Humans
Testosterone
Medical history
Longitudinal Studies
Age of Onset
Aged
Aged, 80 and over
business.industry
Hypogonadism
Penile Erection
androgens
Men
Testosterone (patch)
Middle Aged
questionnaires
Androgen
Endocrinology
testosterone
Bioavailable Testosterone
Geriatrics and Gerontology
Climacteric
business
Subjects
Details
- ISSN :
- 14730790 and 13685538
- Volume :
- 14
- Database :
- OpenAIRE
- Journal :
- The Aging Male
- Accession number :
- edsair.doi.dedup.....688831cc7b241d0349f7cdad061c577e