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Oxethazaine inhibits esophageal squamous cell carcinoma proliferation and metastasis by targeting aurora kinase A

Authors :
Zhuo Bao
Ang Li
Xuebo Lu
Zitong Wang
Yin Yu
Wenjie Wu
Lili Zhao
Bo Li
Xiangyu Wu
Kyle Vaughn Laster
Chengjuan Zhang
Yanan Jiang
Zigang Dong
Kangdong Liu
Source :
Cell Death & Disease. 13
Publication Year :
2022
Publisher :
Springer Science and Business Media LLC, 2022.

Abstract

Esophageal squamous cell carcinoma (ESCC), a malignant neoplasm with high incidence, is a severe global public health threat. The current modalities used for treating ESCC include surgery, chemotherapy, and radiotherapy. Although ESCC management and treatment strategies have improved over the last decade, the overall 5-year survival rate remains

Details

ISSN :
20414889
Volume :
13
Database :
OpenAIRE
Journal :
Cell Death & Disease
Accession number :
edsair.doi.dedup.....6875ca6cace250ba1335a1104e658296
Full Text :
https://doi.org/10.1038/s41419-022-04642-x