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Layer-specific assessment of left ventricular function by utilizing wavelet de-noising: a validation study
- Source :
- Medical & Biological Engineering & Computing. 49:3-13
- Publication Year :
- 2010
- Publisher :
- Springer Science and Business Media LLC, 2010.
-
Abstract
- Regional myocardial function assessment is essential for diagnosis and evaluation of heart disease. The purpose of this study was to enhance the spatial resolution of a speckle tracking echocardiography approach and enable layer-specific analysis of the myocardium. Following validation with software-implemented and mechanical phantoms versus imposed values, short-axis cines were obtained from 50 rats. The cines were post-processed by a speckle tracking commercial program, and the myocardial velocities were processed by a three-dimensional wavelet de-noising program, instead of the built-in smoothing process of the commercial program. Software-implemented phantom measurements yielded rotation errors of 7.5%, 2.9%, and 3.4%, for inner, middle, and outer layers, respectively. Analysis of a shrinking/expanding mechanical phantom yielded strain errors of 3%, 5%, and 7% for the three layers. Bland-Altman analysis showed agreement between the commercial and enhanced programs. Thus, layer-specific analysis is feasible while using echocardiography even on small animals such as rats.
- Subjects :
- Male
Rotation
Phantoms, Imaging
Biomedical Engineering
Speckle tracking echocardiography
Myocardial function
Ventricular Function, Left
Imaging phantom
Rats
Computer Science Applications
Rats, Sprague-Dawley
Speckle pattern
Wavelet
Echocardiography
Models, Animal
Image Processing, Computer-Assisted
Animals
Feasibility Studies
Rotation (mathematics)
Image resolution
Algorithms
Smoothing
Biomedical engineering
Mathematics
Subjects
Details
- ISSN :
- 17410444 and 01400118
- Volume :
- 49
- Database :
- OpenAIRE
- Journal :
- Medical & Biological Engineering & Computing
- Accession number :
- edsair.doi.dedup.....684402342ccd336ac98ee0147797f1d4