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Microglia contribute to the postnatal development of cortical somatostatin-positive inhibitory cells and to whisker-evoked cortical activity

Authors :
Lorenzo Gesuita
Anna Cavaccini
Ali Özgür Argunsah
Emilia Favuzzi
Leena Ali Ibrahim
Tevye Jason Stachniak
Martina De Gennaro
Sebastian Utz
Melanie Greter
Theofanis Karayannis
Source :
Cell Reports. 40:111209
Publication Year :
2022
Publisher :
Elsevier BV, 2022.

Abstract

Microglia play a key role in shaping the formation and refinement of the excitatory network of the brain. However, less is known about whether and how they organize the development of distinct inhibitory networks. We find that microglia are essential for the proper development of somatostatin-positive (SST

Details

ISSN :
22111247
Volume :
40
Database :
OpenAIRE
Journal :
Cell Reports
Accession number :
edsair.doi.dedup.....6835925a580ea8a6f8a388f7a1022cf7
Full Text :
https://doi.org/10.1016/j.celrep.2022.111209