Back to Search
Start Over
Laboratory results in the elderly: the Sydney Older Persons Study
- Source :
- Annals of Clinical Biochemistry: International Journal of Laboratory Medicine. 40:274-279
- Publication Year :
- 2003
- Publisher :
- SAGE Publications, 2003.
-
Abstract
- Background: The use of laboratory intervals based on younger and healthier populations is of questionable validity in older populations. The aim of this study was to examine haematological and biochemical profiles in a sample of community-dwelling older people and to study the impact of age, disease, disability and medications. Methods: Basic haematological and biochemical values were obtained for 338 survivors of a random sample of community-living people aged 75 years or over at time of recruitment. These values were compared to the laboratory reference intervals and the effects of age, disease, medication and disability examined. Results: The distribution of the 35 parameters measured differed from those described by the laboratory reference intervals in all but four of the variables. The values showed few significant age associations but did show associations with disease, disability and drug use. Conclusions: Abnormalities identified in haematological and biochemical testing are not due to age but to age-related illnesses. This is contrary to previous studies reporting a change in haematological and biochemical parameters purely on the basis of age. In the presence of abnormalities, identification and clarification of disease states should be made.
- Subjects :
- Aged, 80 and over
Gerontology
business.industry
Clinical Biochemistry
Australia
General Medicine
Disease
Laboratory results
Nursing Homes
Reference intervals
Older population
Disability Evaluation
Drug Therapy
Residence Characteristics
Chronic Disease
Humans
Medicine
Biochemical testing
business
Older people
Geriatric Assessment
Blood Chemical Analysis
Aged
Subjects
Details
- ISSN :
- 17581001 and 00045632
- Volume :
- 40
- Database :
- OpenAIRE
- Journal :
- Annals of Clinical Biochemistry: International Journal of Laboratory Medicine
- Accession number :
- edsair.doi.dedup.....68312b2f1d3eab8e6b04840f32bc717b
- Full Text :
- https://doi.org/10.1258/000456303321610600