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High Clustering of Acute HCV Infections and High Rate of Associated STIs Among Parisian HIV-Positive Male Patients
- Source :
- International Journal of Antimicrobial Agents, International Journal of Antimicrobial Agents, 2019, 53 (5), pp.678-681. ⟨10.1016/j.ijantimicag.2019.02.002⟩, International Journal of Antimicrobial Agents, Elsevier, 2019, 53 (5), pp.678-681. ⟨10.1016/j.ijantimicag.2019.02.002⟩
- Publication Year :
- 2019
- Publisher :
- HAL CCSD, 2019.
-
Abstract
- International audience; Background - Increasing incidence of hepatitis C virus (HCV) infection in human immunodeficiency virus (HIV)-positive men having sex with men (MSM) has been described in recent years. Phylogenetic analyses of acute HCV infections were undertaken to characterize the dynamics during the epidemic in Paris, and associated sexually transmitted infections (STIs) were evaluated. Methods - Sanger sequencing of polymerase gene was performed. Maximum likelihood phylogenies were reconstructed using FastTree 2.1 under a GTR+CAT model. Transmission chains were defined as clades with a branch probability ≥0.80 and intraclade genetic distances
- Subjects :
- 0301 basic medicine
Male
Human immunodeficiency virus (HIV)
HIV Infections
Hepacivirus
medicine.disease_cause
0302 clinical medicine
[SDV.MHEP.MI]Life Sciences [q-bio]/Human health and pathology/Infectious diseases
Genotype
Prevalence
Cluster Analysis
Pharmacology (medical)
030212 general & internal medicine
Phylogeny
Sanger sequencing
education.field_of_study
Molecular Epidemiology
Transmission (medicine)
Incidence (epidemiology)
virus diseases
General Medicine
Hepatitis C
Homosexuality
Middle Aged
3. Good health
Infectious Diseases
symbols
Microbiology (medical)
Adult
medicine.medical_specialty
Paris
Hepatitis C virus
030106 microbiology
Population
Sexually Transmitted Diseases
Coinfections
03 medical and health sciences
symbols.namesake
Internal medicine
medicine
Disease Transmission, Infectious
Humans
Homosexuality, Male
education
Retrospective Studies
business.industry
HIV
Sequence Analysis, DNA
medicine.disease
Sexually Transmitted Infections
[SDV.SPEE]Life Sciences [q-bio]/Santé publique et épidémiologie
business
Subjects
Details
- Language :
- English
- ISSN :
- 09248579
- Database :
- OpenAIRE
- Journal :
- International Journal of Antimicrobial Agents, International Journal of Antimicrobial Agents, 2019, 53 (5), pp.678-681. ⟨10.1016/j.ijantimicag.2019.02.002⟩, International Journal of Antimicrobial Agents, Elsevier, 2019, 53 (5), pp.678-681. ⟨10.1016/j.ijantimicag.2019.02.002⟩
- Accession number :
- edsair.doi.dedup.....681a12afc5ff9cccd46dbdc5be0d1327