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Real-world comorbidities of atopic dermatitis in the US adult ambulatory population
- Source :
- Journal of the American Academy of Dermatology. 86:835-845
- Publication Year :
- 2022
- Publisher :
- Elsevier BV, 2022.
-
Abstract
- Atopic dermatitis (AD) is a pruritic, inflammatory skin disease associated with various comorbidities. However, comprehensive analyses of real-world comorbidities in adult patients with AD are limited.To characterize the real-world comorbidities associated with adult AD in an ambulatory population.We queried the MarketScan Commercial Claims and Encounters database from January 1, 2017 to December 31, 2017. Multivariable logistic regressions were performed to compare comorbidities in adult patients with AD versus age- and sex-matched controls.A total of 39,779 patients with AD and 353,743 controls were identified. Increased odds of psychiatric conditions, including anxiety (odds ratio [OR] 1.44) and mood disorders (OR 1.31), were observed in patients with AD. Patients with AD had higher likelihoods of autoimmune diseases, including vitiligo (OR 4.44) and alopecia areata (OR 6.01). Adult AD was also associated with infections, including impetigo (OR 9.72), methicillin-resistant Staphylococcus aureus (OR 3.92), and cellulitis (OR 2.52). Patients with AD were more likely to have systemic conditions, including lymphoid/hematopoietic malignancy (OR 1.91), atherosclerosis (OR 1.69), and metabolic syndrome (OR 1.47). For all the above, P .001.Retrospective analysis of health care claims data.Adult AD is associated with various psychiatric and systemic comorbidities, emphasizing the systemic nature of AD and the need for the collaborative management of these patients.
- Subjects :
- Adult
Methicillin-Resistant Staphylococcus aureus
medicine.medical_specialty
education.field_of_study
Impetigo
business.industry
Population
Comorbidity
Dermatology
Vitiligo
Atopic dermatitis
Alopecia areata
medicine.disease
Dermatitis, Atopic
Mood disorders
Internal medicine
Epidemiology
Ambulatory
medicine
Humans
education
business
Retrospective Studies
Subjects
Details
- ISSN :
- 01909622
- Volume :
- 86
- Database :
- OpenAIRE
- Journal :
- Journal of the American Academy of Dermatology
- Accession number :
- edsair.doi.dedup.....68120a9f8174eb83991a23fe794800d7