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Sodium acetate ameliorates cisplatin-induced kidney injury in vitro and in vivo
- Source :
- Chemico-biological interactions. 369
- Publication Year :
- 2022
-
Abstract
- Cisplatin is an effective chemotherapeutic drug against tumors. Studies often report on the improvement of kidney injury by probiotics or short-chain fatty acids (SCFAs); however, the effects of SCFAs on cisplatin-induced kidney injury are rarely studied. The aim of this study is to evaluate the function of sodium acetate on preventing cisplatin-induced kidney injury. Cell viability was detected by MTT assay. SA-β-gal staining was performed to investigate premature senescence. Reactive oxygen species (ROS) production was analyzed by H
- Subjects :
- General Medicine
Toxicology
Subjects
Details
- ISSN :
- 18727786
- Volume :
- 369
- Database :
- OpenAIRE
- Journal :
- Chemico-biological interactions
- Accession number :
- edsair.doi.dedup.....67ffba30c924dec3dd55d6e0d854a966