Back to Search
Start Over
Mesenchymal stem-like cells isolated from human esophageal carcinoma and adjacent non-cancerous tissues
- Source :
- Oncology Letters. 5:179-184
- Publication Year :
- 2012
- Publisher :
- Spandidos Publications, 2012.
-
Abstract
- Mesenchymal stem cells (MSCs) or MSC-like cells have now been isolated from various sites, including different types of tumor tissues. Whether MSCs or MSC-like cells in different tumor tissues possess differentiated biological characteristics remains unclear, and the correlation between MSCs or MSC-like cells and tumors has been a controversial topic. In the present study, we isolated MSC-like cells from human esophageal carcinoma (hEC-MSCs) and adjacent non-cancerous tissues (hECN-MSCs). Although the two types of MSC-like cells were in different microenvironments and had certain differences, they possessed similar morphological properties and surface antigens, including CD13, CD29, CD44 and CD105. Our results indicated that hEC-MSCs and hECN-MSCs are similar in a number of ways. This may have implications for further research on the esophageal carcinoma microenvironment and its pathological mechanism.
- Subjects :
- Cancer Research
Pathology
medicine.medical_specialty
biology
business.industry
Cell
Mesenchymal stem cell
CD44
Articles
Endoglin
Cell cycle
medicine.disease
medicine.anatomical_structure
Oncology
Antigen
Carcinoma
medicine
biology.protein
business
Stem cell transplantation for articular cartilage repair
Subjects
Details
- ISSN :
- 17921082 and 17921074
- Volume :
- 5
- Database :
- OpenAIRE
- Journal :
- Oncology Letters
- Accession number :
- edsair.doi.dedup.....67a8389e79dce8e475241336d6c980d0