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Voice disorders in residual paracoccidioidomycosis in upper airways and digestive tract
- Source :
- Revista Iberoamericana de Micología. 34:180-184
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- Background Paracoccidioidomycosis (PCM) is a systemic mycosis of acute and chronic evolution, caused by species belonging to the genus Paracoccidioides. It is considered the most prevalent systemic endemic mycosis in Latin America, with cases in the tropical and subtropical regions. Residual PCM refers to the fibrotic scar sequelae resulting from the disease treatment which, when associated with collagen accumulation, leads to functional and anatomic alterations in the organs. Aims The aim of this study was to evaluate the vocal function of patients with residual PCM in upper airways and digestive tract. Methods We performed a cross-sectional study in 2010 in a cohort of 21 patients with residual PCM in upper airways and digestive tract. Results The average age was 49.48 ± 9.1 years, and only two (9.5%) patients were female. The study was performed in the 1–113 month-period (median 27) after the end of drug treatment. Five (23.8%) patients had alterations in the larynx as a sequela of the disease. However, all patients had vocal changes in vocal auditory perceptual analysis by GRBASI scale. The computerized acoustic analysis using the software Vox Metria, showed that 11 patients (52.4%) presented alterations in jitter, 15 (71.4%) in shimmer, 8 (38.1%) in F0, 4 (19%) in glottal to noise excitation (GNE), 7 (33.3%) in the presence of noise and 12 (57.1%) in the presence of vibratory irregularity. Conclusions The great frequency of alterations in residual PCM suggests that the patients in such phase could benefit from a multidisciplinary treatment, offering them integral monitoring of the disease, including speech rehabilitation after the PCM is healed.
- Subjects :
- 0301 basic medicine
Larynx
medicine.medical_specialty
Pathology
Collagen accumulation
Paracoccidioidomycosis
business.industry
030231 tropical medicine
030106 microbiology
Sequela
Disease
medicine.disease
Microbiology
Gastroenterology
03 medical and health sciences
0302 clinical medicine
Infectious Diseases
medicine.anatomical_structure
Internal medicine
Vocal function
Cohort
medicine
Digestive tract
business
Subjects
Details
- ISSN :
- 11301406
- Volume :
- 34
- Database :
- OpenAIRE
- Journal :
- Revista Iberoamericana de Micología
- Accession number :
- edsair.doi.dedup.....679cd636fc95b68b795f14c80b584a01