Back to Search
Start Over
Assessment of the Progression of Post-stroke Depression in Ischemic Stroke Patients using the Patient Health Questionnaire-9
- Source :
- J Stroke Cerebrovasc Dis
- Publication Year :
- 2020
-
Abstract
- BACKGROUND: Post-stroke depression (PSD) affects one-third of stroke patients and is linked with higher stroke morbidity, mortality, and recurrence. Current guidelines do not direct when to screen for PSD, and predictors of PSD are not well understood. We sought to understand progression of PSD symptoms early after ischemic stroke, identify predictors of PSD, and describe the use of antidepressants in PSD. METHODS: We collected demographic, clinical, and PSD (Patient Health Questionnaire-9; PHQ-9) data from ischemic stroke patients hospitalized at our Comprehensive Stroke Center and followed up in our clinic. PHQ-9 was obtained during hospitalization and again in clinic within 180 days of discharge. We performed univariate analysis and logistic regression to detect variables associated with PSD. RESULTS: Among 201 patients, PSD symptoms (PHQ-9 > 4) were identified in 30% of patients during hospitalization and 46% during follow-up (54% of which had no symptoms during hospitalization). At follow-up, 36% were worse by PHQ-9 category. In univariate analysis, follow-up modified Rankin Scale (mRS) ≥2 (p=0.03) and antidepressant prescription (p
- Subjects :
- Male
medicine.medical_specialty
Time Factors
Patient Health Questionnaire
Logistic regression
Risk Assessment
Article
Brain Ischemia
03 medical and health sciences
Disability Evaluation
0302 clinical medicine
Modified Rankin Scale
Predictive Value of Tests
Risk Factors
Internal medicine
mental disorders
medicine
Secondary Prevention
Humans
Medical prescription
Stroke
Depression (differential diagnoses)
Aged
Univariate analysis
business.industry
Depression
musculoskeletal, neural, and ocular physiology
Rehabilitation
Middle Aged
medicine.disease
Antidepressive Agents
Hospitalization
Affect
Treatment Outcome
nervous system
Ischemic stroke
Disease Progression
Surgery
Female
Neurology (clinical)
Cardiology and Cardiovascular Medicine
business
030217 neurology & neurosurgery
psychological phenomena and processes
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- J Stroke Cerebrovasc Dis
- Accession number :
- edsair.doi.dedup.....677943a1491eec9ef64c9cc384ada8d2