Induction of apoptosis in SGC-7901 cells by iridium(III) complexes via endoplasmic reticulum stress-mitochondrial dysfunction pathway

Authors :: Jiawen, Wang
Haimei, Liu
Xiaoyun, Wu
Chuanling, Shi
Wenlong, Li
Yuhan, Yuan
Yunjun, Liu
Degang, Xing
Source :: JBIC Journal of Biological Inorganic Chemistry. 27:455-469
Publication Year :: 2022
Publisher :: Springer Science and Business Media LLC, 2022.
Abstract: This study was intended to evaluate the anticancer activity of three newly synthesized iridium(III) complexes [Ir(ppy)

Subjects :: Bromides
Antineoplastic Agents
Apoptosis
Endoplasmic Reticulum Stress
Iridium
Biochemistry
Mitochondria
Inorganic Chemistry
Mice
Coordination Complexes
Cell Line, Tumor
NIH 3T3 Cells
Animals
Humans
Reactive Oxygen Species
Cell Proliferation
Phenanthrolines

Tools