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Ebola virus disease: emergence, outbreak and future directions
- Source :
- British Medical Bulletin. 117:95-106
- Publication Year :
- 2016
- Publisher :
- Oxford University Press (OUP), 2016.
-
Abstract
- Background The West African Ebola crisis of 2013-15 is the largest outbreak since Ebola was first identified; Ebola has high case fatality. Sources of data Pubmed with terms 'Ebola' and 'EVD' from January 1976 to June 2015. Public domain material. Areas of agreement The emergence of Ebola virus, virology, clinical features and the major elements of the 2014 outbreak and the public health response. Ebola is only transmitted by direct contact with infected individuals (including dead bodies) and their body fluids. Methods of control in hospitals and burials, and protection of healthcare workers are well established if difficult to achieve. Areas of contention There remains uncertainty surrounding specific public health interventions and novel therapies (including vaccines). How best to reduce transmission in the community during major outbreaks remains unclear. Future directions The potential of vaccine and therapeutic candidates in the event of another outbreak on this scale. . Search strategy We searched all entries on the MedLine database/PubMed from 1976-2015 with the MeSH terms 'ebola', 'EVD', 'haemorrhagic fever'. We also reviewed publically available information via institutional websites from Governmental, NGOs and news organizations pertaining to the above search terms.
- Subjects :
- 0301 basic medicine
medicine.medical_specialty
viruses
medicine.disease_cause
Disease Outbreaks
03 medical and health sciences
0302 clinical medicine
Health care
Case fatality rate
Epidemiology
medicine
Humans
030212 general & internal medicine
Ebolavirus
Ebola virus
business.industry
Transmission (medicine)
Public health
virus diseases
Outbreak
General Medicine
Hemorrhagic Fever, Ebola
medicine.disease
Virology
Africa, Western
030104 developmental biology
Geography
Medical emergency
business
Public Health Administration
Subjects
Details
- ISSN :
- 14718391 and 00071420
- Volume :
- 117
- Database :
- OpenAIRE
- Journal :
- British Medical Bulletin
- Accession number :
- edsair.doi.dedup.....66e874f140e6712cf1137c14a02a8c35