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Additional file 1 of DNA methylation profiling identifies two distinct subgroups in breast cancers with low hormone receptor expression, mainly associated with HER2 amplification status

Authors :
Jurmeister, Philipp
Weber, Karsten
Villegas, Sonia
Karn, Thomas
Untch, Michael
Thieme, Anne
Müller, Volkmar
Taube, Eliane
Fasching, Peter
Schmitt, Wolfgang D.
Marmé, Frederik
Stickeler, Elmar
Sinn, Bruno V.
Jank, Paul
Schem, Christian
Klauschen, Frederick
van Mackelenbergh, Marion
Denkert, Carsten
Loibl, Sibylle
Capper, David
Publication Year :
2021
Publisher :
figshare, 2021.

Abstract

Additional file 1. Fig. S1: t-distributed stochastic neighbor embedding (t-SNE) plots showing the estimated tumor purity of The Cancer Genome Atlas samples based on manual estimation using light microscopy (a), RNAseq data (ESTIMATE; b), copy number variations (ABSOLUTE; c), DNA methylation (LUMP; d) and a combined score (CPE; e).

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....669a44072bf64319390c6a5e8cdbdf97
Full Text :
https://doi.org/10.6084/m9.figshare.16727591