Back to Search
Start Over
Bullous Drug Reactions
- Source :
- Acta Dermato-Venereologica, Vol 100, Iss 5, p adv00057 (2020)
- Publication Year :
- 2020
- Publisher :
- Medical Journals Sweden AB, 2020.
-
Abstract
- Bullous drug eruptions are infrequent, but because they pose a challenge both to affected patients and to treating physicians they are considered to be the most severe cutaneous adverse reactions (SCAR). It is important to recognize these conditions and to differentiate them from other clinical entities involving blister formation. There may be early signs and symptoms that indicate a severe bullous drug eruption even before blisters and erosions of the skin and mucous membranes become obvious. Once the diagnosis is suspected, appropriate diagnostic procedures and adequate management must be initiated. The latter includes identification of the potentially inducing drug, although it should be taken into account that not all cases of bullous eruptions are drug-induced. In cases with drug causality the potentially culprit agent must be withdrawn, while in cases with other aetiology the underlying condition, e.g. an infection, must be treated appropriately. In addition to best supportive care, immunomodulating therapy may be considered.
- Subjects :
- Male
Drug
medicine.medical_specialty
Bullous eruptions
Early signs
media_common.quotation_subject
Dermatology
Risk Assessment
Severity of Illness Index
Immunomodulation
03 medical and health sciences
0302 clinical medicine
toxic epidermal necrolysis
Germany
medicine
Humans
Drug reaction
media_common
Skin Diseases, Vesiculobullous
integumentary system
business.industry
Incidence
severe cutaneous adverse reaction
Biopsy, Needle
General Medicine
Prognosis
medicine.disease
Immunohistochemistry
generalized bullous fixed drug eruption
Toxic epidermal necrolysis
Drug eruption
Treatment Outcome
RL1-803
Stevens-Johnson Syndrome
030221 ophthalmology & optometry
Etiology
Female
Drug Eruptions
business
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 16512057
- Volume :
- 100
- Database :
- OpenAIRE
- Journal :
- Acta Dermato Venereologica
- Accession number :
- edsair.doi.dedup.....6683d7f2714129e2274514da9a64a8fe