Bromopyrrole alkaloids from marine sponges of the genus Agelas

Four new bromopyrrole alkaloids, nagelamides O (1) and P (2) and mukanadins E (3) and F (4), were isolated from three collections of Okinawan marine sponges of the genus Agelas. The structures and stereochemistry of 1−4 were elucidated on the basis of their spectroscopic data.