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Myocardial failure in experimental hypothermia
- Source :
- Circulation research. 5(1)
- Publication Year :
- 1957
-
Abstract
- Hypothermic animals subjected to total venous inflow occlusion and open cardiotomy develop elevations in right atrial mean pressure and postmortem evidences of myocardial failure. Acetyl strophanthidin, given before inflow stasis, prevented myocardial failure and increased survival. Myocardial failure was attributed to anoxia resulting from decreased coronary blood flow and alterations in the oxygen content of the blood supplying the myocardium. Perfusion of the coronary system with small quantities of oxygenated blood obtained from donor animals permitted open cardiotomy with survival.
- Subjects :
- Heart Failure
medicine.medical_specialty
Myocardial Failure
Physiology
business.industry
medicine.medical_treatment
Mean pressure
Thoracic Surgery
Blood flow
Hypothermia
Right atrial
Internal medicine
Anesthesia
cardiovascular system
medicine
Cardiology
Humans
medicine.symptom
Cardiac Surgical Procedures
Cardiology and Cardiovascular Medicine
business
Cardiotomy
Oxygen content
Perfusion
Subjects
Details
- ISSN :
- 00097330
- Volume :
- 5
- Issue :
- 1
- Database :
- OpenAIRE
- Journal :
- Circulation research
- Accession number :
- edsair.doi.dedup.....6635e52d5016064b54486e77f3eaf033