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Do Men and Women Respond Differently to Percutaneous Renal Artery Interventions?

Authors :
Fernando Cura
Jorge A. Belardi
Mariano Albertal
Jorge Thierer
Gerardo Nau
Lucio Padilla
Source :
Angiology. 61:216-221
Publication Year :
2009
Publisher :
SAGE Publications, 2009.

Abstract

Background: Women have higher risk of contrast-induced nephropathy than men. The purpose of this study was to determine the relative impact of gender on long-term renal function after percutaneous renal interventions (PRI). Methods and Results: We included all patients undergoing PRI. Men (n = 72) and women (n = 28) had similar age, men had more diabetes, coronary and peripheral artery disease, higher serum creatinine and similar glomerular filtration rate (GFR), and prevalence of chronic kidney disease (CKD) stage ≥3 when compared with females. At follow-up, men had a significant improvement in GFR and systolic blood pressure, while females did not. The presence of severe CKD and male gender were the only predictors of long-term GFR improvement. Conclusion: Male patients and patients with poor baseline renal function showed an important benefit with PRI, suggesting that it is not too late for renal revascularization if properly indicated.

Details

ISSN :
19401574 and 00033197
Volume :
61
Database :
OpenAIRE
Journal :
Angiology
Accession number :
edsair.doi.dedup.....65b2ed13635f3e2469bef5f995c631dc
Full Text :
https://doi.org/10.1177/0003319709337306