Additional file 1 of Farnesal-loaded pH-sensitive polymeric micelles provided effective prevention and treatment on dental caries

Additional file 1: Figure S1.1H NMR and 13C NMR spectra of synthetic compound 1: tert-butyl 2-(2-(2-hydroxyethoxy)acetyl)hydrazine-1-carboxylate (HO-PEG-NHNH-Boc). Figure S2.1H NMR, 13C NMR and 31P NMR spectra of synthetic compound 2: sodium 2,2-dimethyl-4,7,13-trioxo-3,9,12-trioxa-5,6-diazatetradecan-14-yl hydrogen diphosphate (PPi-PEG-NHNH-Boc). Figure S3.1H NMR and 13C NMR spectra of synthetic compound 3: sodium 2-(2-(2-hydrazinyl-2-oxoethoxy)ethoxy)-2-oxoethyl hydrogen diphosphate (PPi-PEG-NHNH2). Figure S4.1H NMR and 13C NMR spectra of synthetic compound 4: sodium 2-oxo-2-(2-(2-oxo-2-(2-((2E,6E)-3,7,11-trimethyldodeca-2,6,10-trien-1-ylidene)hydrazinyl)ethoxy)ethoxy)ethyl hydrogen diphosphate (PPi-PEG-hyd-Far)) is available in the online version of this article.