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Beneficial Effects of Non-Invasive Ventilation After Extubation in Obese or Overweight Patients : A Post-Hoc Analysis of a Randomized Clinical Trial
- Source :
- American Journal of Respiratory and Critical Care Medicine, American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2021, ⟨10.1164/rccm.202106-1452OC⟩
- Publication Year :
- 2021
- Publisher :
- HAL CCSD, 2021.
-
Abstract
- RATIONALE Whereas non-invasive ventilation (NIV) may prevent reintubation in patients at high-risk of extubation failure in intensive care units (ICUs), this oxygenation strategy has not been specifically assessed in obese patients. OBJECTIVES We hypothesized that NIV may decrease the risk of reintubation in obese patients compared with high-flow nasal oxygen (HFNO). METHODS Post-hoc analysis of a multicenter, randomized, controlled trial (not pre-specified) comparing NIV alternating with HFNO versus HFNO alone after extubation, with the aim of assessing NIV effects according to patient body-mass index (BMI). MEASUREMENTS AND MAIN RESULTS Among 623 patients at high-risk of extubation failure, 206 (33%) were obese (BMI≥30 kg/m2), 204 (33%) were overweight (25≤BMI
- Subjects :
- Pulmonary and Respiratory Medicine
business.industry
Airway Extubation
Overweight
Critical Care and Intensive Care Medicine
Intensive care unit
[SDV.MHEP.PSR]Life Sciences [q-bio]/Human health and pathology/Pulmonology and respiratory tract
3. Good health
law.invention
03 medical and health sciences
0302 clinical medicine
030228 respiratory system
Randomized controlled trial
law
Intensive care
Anesthesia
Post-hoc analysis
Breathing
medicine
030212 general & internal medicine
medicine.symptom
Underweight
business
ComputingMilieux_MISCELLANEOUS
Subjects
Details
- Language :
- English
- ISSN :
- 1073449X and 15354970
- Database :
- OpenAIRE
- Journal :
- American Journal of Respiratory and Critical Care Medicine, American Journal of Respiratory and Critical Care Medicine, American Thoracic Society, 2021, ⟨10.1164/rccm.202106-1452OC⟩
- Accession number :
- edsair.doi.dedup.....65393e694bdd3c8dcbbd2c558e992c4c
- Full Text :
- https://doi.org/10.1164/rccm.202106-1452OC⟩