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Prospective evaluation of clinical scoring systems in infants with bronchiolitis admitted to the intensive care unit
- Source :
- European journal of clinical microbiologyinfectious diseases : official publication of the European Society of Clinical Microbiology. 31(10)
- Publication Year :
- 2012
-
Abstract
- The objective of this investigation was to compare different scoring systems to assess the severity of illness in infants with bronchiolitis admitted to a tertiary paediatric intensive care unit (PICU). Over an 18-year period (1990–2007), infants with bronchiolitis aged up to 12 months and admitted to the PICU were prospectively scored using the Pediatric Risk of Mortality III (PRISM III) score, the Organ System Failure (OSF) score and the Acute Physiologic Score for Children (APSC) within 24 h. Infants were compared as to whether or not bronchiolitis was associated with respiratory syncytial virus (RSV). There was no difference between 113 RSV-positive and 80 RSV-negative infants regarding gestational age, birth weight, rate of premature delivery or bronchopulmonary dysplasia (BPD). The PRISM III score differed significantly between RSV-positive and RSV-negative cases (3.27 ± 0.39 vs. 1.96 ± 0.44, p = 0.006), as did the OSF score (0.56 ± 0.05 vs. 0.35 ± 0.06, p = 0.049) and the APSC (5.16 ± 0.46 vs. 4.1 ± 0.53, p = 0.048). All scores were significantly higher in the subgroup with mechanical ventilation (p
- Subjects :
- Microbiology (medical)
Pediatrics
medicine.medical_specialty
Time Factors
medicine.medical_treatment
Birth weight
Gestational Age
Respiratory Syncytial Virus Infections
Intensive Care Units, Pediatric
Sensitivity and Specificity
Severity of Illness Index
law.invention
law
Severity of illness
Risk of mortality
Medicine
Birth Weight
Humans
Prospective Studies
Bronchopulmonary Dysplasia
Mechanical ventilation
business.industry
Infant, Newborn
Gestational age
Infant
General Medicine
medicine.disease
Intensive care unit
Respiration, Artificial
Respiratory Syncytial Viruses
Infectious Diseases
Bronchopulmonary dysplasia
ROC Curve
Bronchiolitis
business
Infant, Premature
Subjects
Details
- ISSN :
- 14354373
- Volume :
- 31
- Issue :
- 10
- Database :
- OpenAIRE
- Journal :
- European journal of clinical microbiologyinfectious diseases : official publication of the European Society of Clinical Microbiology
- Accession number :
- edsair.doi.dedup.....6519571f2f95fd686550c62b55192adc