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Towards non-invasive diagnostic techniques for early detection of acute renal transplant rejection: A review
- Source :
- The Egyptian Journal of Radiology and Nuclear Medicine, Vol 48, Iss 1, Pp 257-269 (2017)
- Publisher :
- The Egyptian Society of Radiology and Nuclear Medicine. Production and hosting by Elsevier.
-
Abstract
- The kidney is a very important complicated filtering organ of the body. When the kidney reaches stage 5 chronic kidney disease, end stage renal failure, the preeminent therapy is renal transplantation. Although it is the best form of treatment, lack of kidney donors is still challenging. Therefore, all efforts should be employed to prolong the survival rate of the transplanted kidney. However, graft dysfunction (e.g., acute rejection) is one of the serious barriers to long term kidney transplant survival. Currently, graft dysfunction’s gold standard of diagnosis is renal biopsy. Although renal biopsy is helpful, it is not preferred due to its invasive nature, high morbidity rates, and expensiveness. Therefore, noninvasive imaging techniques have become the subject of extensive research and interest, giving a strong promise to replace, or at least to decrease, biopsy usage in diagnosing graft dysfunction. This survey will discuss not only the current diagnosis and treatment of graft dysfunction but also the state-of-the-art imaging techniques in detecting acute renal transplant rejection.
- Subjects :
- lcsh:Medical physics. Medical radiology. Nuclear medicine
Nephrology
medicine.medical_specialty
lcsh:R895-920
030232 urology & nephrology
Imaging techniques
Artificial kidney
030218 nuclear medicine & medical imaging
Kidney transplantation
03 medical and health sciences
0302 clinical medicine
Internal medicine
Chronic kidney disease
Biopsy
medicine
Radiology, Nuclear Medicine and imaging
Intensive care medicine
Survival rate
Kidney
medicine.diagnostic_test
business.industry
Acute renal rejection
medicine.disease
Transplantation
medicine.anatomical_structure
surgical procedures, operative
Radiology Nuclear Medicine and imaging
Renal biopsy
business
Subjects
Details
- Language :
- English
- ISSN :
- 0378603X
- Database :
- OpenAIRE
- Journal :
- The Egyptian Journal of Radiology and Nuclear Medicine
- Accession number :
- edsair.doi.dedup.....64e4528349ada9b31287b5603f7b6ef7
- Full Text :
- https://doi.org/10.1016/j.ejrnm.2016.11.005