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COVID-19 in children. II: Pathogenesis, disease spectrum and management
COVID-19 in children. II: Pathogenesis, disease spectrum and management
- Source :
- Journal of Paediatrics and Child Health
- Publication Year :
- 2021
-
Abstract
- The global disruption of the COVID-19 pandemic has impacted the life of every child either directly or indirectly. This review explores the pathophysiology, immune response, clinical presentation and treatment of COVID-19 in children, summarising the most up-to-date data including recent developments regarding variants of concern. The acute infection with SARS-CoV-2 is generally mild in children, whilst the post-infectious manifestations, including paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS) and 'long COVID' in children, are more complex. Given that most research on COVID-19 has focused on adult cohorts and that clinical manifestations, treatment availability and impacts differ markedly in children, research that specifically examines COVID-19 in children needs to be prioritised.
- Subjects :
- medicine.medical_specialty
2019-20 coronavirus outbreak
Coronavirus disease 2019 (COVID-19)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
Acute infection
Review Article
SARS‐CoV‐2
Pathogenesis
Post-Acute COVID-19 Syndrome
COVID‐19
PIMS‐TS
Pandemic
medicine
Humans
Child
Intensive care medicine
Review Articles
Pandemics
SARS-CoV-2
business.industry
Disease spectrum
COVID-19
Systemic Inflammatory Response Syndrome
virology
Coronavirus
Pediatrics, Perinatology and Child Health
business
management
Subjects
Details
- Language :
- English
- Database :
- OpenAIRE
- Journal :
- Journal of Paediatrics and Child Health
- Accession number :
- edsair.doi.dedup.....64d1c0d3e993b639483d5fc9da494a99