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Lupus mastitis as a first manifestation of systemic disease: About two cases with a review of the literature
- Source :
- European Journal of Radiology. 92:124-131
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- Lupus mastitis is an uncommon manifestation of systemic lupus erythematosus (SLE) that affects the subcutaneous fat in the breast, much like lupus panniculitis, but additionally involves the mammary gland. We report on two women for whom lupus mastitis was the initial manifestation of SLE and provide a literature review of 34 additional cases reported in the Anglo-Saxon and French literature since 1971, making this the largest review to date. Lupus mastitis (LM) can manifest clinically as subcutaneous masses that may be painful, or may present cutaneous involvement such as thickening and discolouration. The radiologic manifestations of LM are broad and include calcifications, masses and asymmetries. Most often, excluding malignancy requires percutaneous biopsy, with histologic findings that are virtually pathognomonic for SLE. Thus, surgery is avoided and medical management can begin, antimalarial drugs and corticosteroids in most cases.
- Subjects :
- Systemic disease
Pathology
medicine.medical_specialty
Mammary gland
Subcutaneous Fat
Mastitis
Malignancy
030207 dermatology & venereal diseases
03 medical and health sciences
0302 clinical medicine
immune system diseases
Pathognomonic
Panniculitis, Lupus Erythematosus
medicine
Humans
Lupus Erythematosus, Systemic
Radiology, Nuclear Medicine and imaging
Breast
skin and connective tissue diseases
Aged
Systemic lupus erythematosus
business.industry
Biopsy, Needle
General Medicine
Middle Aged
medicine.disease
Lupus Panniculitis
medicine.anatomical_structure
030220 oncology & carcinogenesis
Female
business
Anti-SSA/Ro autoantibodies
Subjects
Details
- ISSN :
- 0720048X
- Volume :
- 92
- Database :
- OpenAIRE
- Journal :
- European Journal of Radiology
- Accession number :
- edsair.doi.dedup.....64c25b0dad2da213cf25eda347cb56bb