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The association between adult attained height and sitting height with mortality in the European prospective investigation into cancer and nutrition (EPIC)
- Source :
- PLoS ONE [E], 12(3). Public Library of Science, PLoS ONE, Sawada, N, Wark, P A, Merritt, M A, Tsugane, S, Ward, H A, Rinaldi, S, Weiderpass, E, Dartois, L, His, M, Boutron-Ruault, M-C, Turzanski-Fortner, R, Kaaks, R, Overvad, K, Redondo, M L, Travier, N, Molina-Portillo, E, Dorronsoro, M, Cirera, L, Ardanaz, E, Perez-Cornago, A, Trichopoulou, A, Lagiou, P, Valanou, E, Masala, G, Pala, V, Hm Peeters, P, T van der Schouw, Y, Melander, O, Manjer, J, da Silva, M, Skeie, G, Tjønneland, A, Olsen, A, J Gunter, M, Riboli, E & J Cross, A 2017, ' The association between adult attained height and sitting height with mortality in the European Prospective Investigation into Cancer and Nutrition (EPIC) ', PLOS ONE, vol. 12, no. 3, e0173117 . https://doi.org/10.1371/journal.pone.0173117, Sawada, N, Wark, P A, Merritt, M A, Tsugane, S, Ward, H A, Rinaldi, S, Weiderpass, E, Dartois, L, His, M, Boutron-Ruault, M-C, Turzanski-Fortner, R, Kaaks, R, Overvad, K, Redondo, M-L, Travier, N, Molina-Portillo, E, Dorronsoro, M, Cirera, L, Ardanaz, E, Perez-Cornago, A, Trichopoulou, A, Lagiou, P, Valanou, E, Masala, G, Pala, V, Hm Peeters, P, T van der Schouw, Y, Melander, O, Manjer, J, da Silva, M, Skeie, G, Tjønneland, A, Olsen, A, J Gunter, M, Riboli, E & J Cross, A 2017, ' The association between adult attained height and sitting height with mortality in the European Prospective Investigation into Cancer and Nutrition (EPIC) ', P L o S One, vol. 12, no. 3, pp. e0173117 . https://doi.org/10.1371/journal.pone.0173117, PLoS ONE, Vol 12, Iss 3, p e0173117 (2017)
- Publication Year :
- 2017
-
Abstract
- Source at https://doi.org/10.1371/journal.pone.0173117 Adult height and sitting height may reflect genetic and environmental factors, including early life nutrition, physical and social environments. Previous studies have reported divergent associations for height and chronic disease mortality, with positive associations observed for cancer mortality but inverse associations for circulatory disease mortality. Sitting height might be more strongly associated with insulin resistance; however, data on sitting height and mortality is sparse. Using the European Prospective Investigation into Cancer and Nutrition study, a prospective cohort of 409,748 individuals, we examined adult height and sitting height in relation to all-cause and cause-specific mortality. Height was measured in the majority of participants; sitting height was measured in ~253,000 participants. During an average of 12.5 years of follow-up, 29,810 deaths (11,931 from cancer and 7,346 from circulatory disease) were identified. Hazard ratios (HR) with 95% confidence intervals (CI) for death were calculated using multivariable Cox regression within quintiles of height. Height was positively associated with cancer mortality (men: HRQ5 vs. Q1 = 1.11, 95%CI = 1.00–1.24; women: HRQ5 vs. Q1 = 1.17, 95%CI = 1.07–1.28). In contrast, height was inversely associated with circulatory disease mortality (men: HRQ5 vs. Q1 = 0.63, 95%CI = 0.56–0.71; women: HRQ5 vs. Q1 = 0.81, 95%CI = 0.70–0.93). Although sitting height was not associated with cancer mortality, it was inversely associated with circulatory disease (men: HRQ5 vs. Q1 = 0.64, 95%CI = 0.55–0.75; women: HRQ5 vs. Q1 = 0.60, 95%CI = 0.49–0.74) and respiratory disease mortality (men: HRQ5 vs. Q1 = 0.45, 95%CI = 0.28–0.71; women: HRQ5 vs. Q1 = 0.60, 95%CI = 0.40–0.89). We observed opposing effects of height on cancer and circulatory disease mortality. Sitting height was inversely associated with circulatory disease and respiratory disease mortality.
- Subjects :
- Male
Respiratory Tract Diseases
Social Sciences
Biochemistry
Vascular Medicine
Habits
0302 clinical medicine
Sociology
Neoplasms
Smoking Habits
Medicine and Health Sciences
Medicine
Coronary Heart Disease
Public and Occupational Health
030212 general & internal medicine
Prospective Studies
Prospective cohort study
2. Zero hunger
Medicine(all)
Multidisciplinary
Schools
Alcohol Consumption
VDP::Medisinske Fag: 700::Helsefag: 800::Samfunnsmedisin, sosialmedisin: 801
Agricultural and Biological Sciences(all)
Incidence (epidemiology)
Cancer Risk Factors
Incidence
Hazard ratio
Middle Aged
Prognosis
3. Good health
European Prospective Investigation into Cancer and Nutrition
Stroke
Europe
Multicenter Study
Neurology
Oncology
Cardiovascular Diseases
030220 oncology & carcinogenesis
Female
Research Article
Adult
medicine.medical_specialty
General Science & Technology
Science
Cerebrovascular Diseases
Cardiology
Education
03 medical and health sciences
MD Multidisciplinary
Journal Article
Humans
Survival analysis
Educational Attainment
Ischemic Stroke
Nutrition
Aged
Behavior
business.industry
Proportional hazards model
Biochemistry, Genetics and Molecular Biology(all)
Cancer
Biology and Life Sciences
Physical Activity
medicine.disease
Hormonal Causes of Cancer
Survival Analysis
Confidence interval
Body Height
Diet
Physical therapy
VDP::Medical disciplines: 700::Health sciences: 800::Community medicine, Social medicine: 801
business
Demography
Genetics and Molecular Biology(all)
Subjects
Details
- Language :
- English
- ISSN :
- 19326203
- Database :
- OpenAIRE
- Journal :
- PLoS ONE [E], 12(3). Public Library of Science, PLoS ONE, Sawada, N, Wark, P A, Merritt, M A, Tsugane, S, Ward, H A, Rinaldi, S, Weiderpass, E, Dartois, L, His, M, Boutron-Ruault, M-C, Turzanski-Fortner, R, Kaaks, R, Overvad, K, Redondo, M L, Travier, N, Molina-Portillo, E, Dorronsoro, M, Cirera, L, Ardanaz, E, Perez-Cornago, A, Trichopoulou, A, Lagiou, P, Valanou, E, Masala, G, Pala, V, Hm Peeters, P, T van der Schouw, Y, Melander, O, Manjer, J, da Silva, M, Skeie, G, Tjønneland, A, Olsen, A, J Gunter, M, Riboli, E & J Cross, A 2017, ' The association between adult attained height and sitting height with mortality in the European Prospective Investigation into Cancer and Nutrition (EPIC) ', PLOS ONE, vol. 12, no. 3, e0173117 . https://doi.org/10.1371/journal.pone.0173117, Sawada, N, Wark, P A, Merritt, M A, Tsugane, S, Ward, H A, Rinaldi, S, Weiderpass, E, Dartois, L, His, M, Boutron-Ruault, M-C, Turzanski-Fortner, R, Kaaks, R, Overvad, K, Redondo, M-L, Travier, N, Molina-Portillo, E, Dorronsoro, M, Cirera, L, Ardanaz, E, Perez-Cornago, A, Trichopoulou, A, Lagiou, P, Valanou, E, Masala, G, Pala, V, Hm Peeters, P, T van der Schouw, Y, Melander, O, Manjer, J, da Silva, M, Skeie, G, Tjønneland, A, Olsen, A, J Gunter, M, Riboli, E & J Cross, A 2017, ' The association between adult attained height and sitting height with mortality in the European Prospective Investigation into Cancer and Nutrition (EPIC) ', P L o S One, vol. 12, no. 3, pp. e0173117 . https://doi.org/10.1371/journal.pone.0173117, PLoS ONE, Vol 12, Iss 3, p e0173117 (2017)
- Accession number :
- edsair.doi.dedup.....645a7b91dd9ccbc2ff4d9074e3e85ecf