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Fighting Fire with Fiber: Preventing T Cell Infiltration in Diabetes
- Source :
- Cell Metabolism. 26:8-10
- Publication Year :
- 2017
- Publisher :
- Elsevier BV, 2017.
-
Abstract
- Diet can alter the gut microbiota and shift its production of metabolites, which affect systemic immune function. In Nature Immunology, Mariño et al. (2017) explore diet-gut microbiome interactions in type 1 diabetes and identify mechanisms by which short-chain fatty acids prevent T cell destruction of pancreatic β-cells.
- Subjects :
- Dietary Fiber
0301 basic medicine
Physiology
T-Lymphocytes
Gut flora
digestive system
03 medical and health sciences
Immune system
Insulin-Secreting Cells
Diabetes mellitus
medicine
Animals
Humans
Microbiome
Molecular Biology
Type 1 diabetes
biology
Gastrointestinal Microbiome
T cell infiltration
Cell Biology
Fatty Acids, Volatile
medicine.disease
biology.organism_classification
Diabetes Mellitus, Type 1
030104 developmental biology
Immunology
Subjects
Details
- ISSN :
- 15504131
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- Cell Metabolism
- Accession number :
- edsair.doi.dedup.....645607acb296f144e2ee685e1e28d36c
- Full Text :
- https://doi.org/10.1016/j.cmet.2017.06.012