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Quantitative assessment of erector spinae muscles in patients with Mycobacterium avium complex lung disease
- Source :
- Respiratory medicine. 145
- Publication Year :
- 2018
-
Abstract
- Background and objective No reports exist regarding skeletal muscle involvement in patients with Mycobacterium avium complex lung disease (MAC-LD). The cross-sectional area of the erector spinae muscles (ESMCSA) reflects physical activity and can be assessed by computed tomography (CT). We investigated the relationship between ESMCSA and physiological parameters and prognosis in MAC-LD patients. Material and methods In this prospective observational study, the ESMCSA was measured on single-slice axial CT images. MAC-LD patients and sex- and age-matched controls (non-MAC-LD participants) were evaluated. We evaluated the relationship between the ESMCSA and physiological parameters and prognosis. Results A total of 260 patients (209 female; median age, 69 years; 190 with nodular/bronchiectatic disease; 74 with cavitary lesions) were enrolled. The ESMCSA was not different between MAC-LD patients and controls. In MAC-LD patients, the ESMCSA was significantly associated with age, body mass index (BMI), pulmonary function, CT severity, and health-related quality of life (HRQL). Multivariate Cox proportional hazards analyses revealed that an ESMCSA Conclusions Although the prognostic impact was limited, ESMCSA was significantly associated with HRQL and prognostic physiological parameters, such as BMI and pulmonary function.
- Subjects :
- Pulmonary and Respiratory Medicine
Lung Diseases
Male
medicine.medical_specialty
Disease
Gastroenterology
Severity of Illness Index
Pulmonary function testing
Body Mass Index
03 medical and health sciences
0302 clinical medicine
Quality of life
Internal medicine
Erector spinae muscles
medicine
Humans
In patient
030212 general & internal medicine
Prospective Studies
Lung
Aged
Mycobacterium avium-intracellulare Infection
Proportional hazards model
business.industry
Back Muscles
Age Factors
Middle Aged
Prognosis
030228 respiratory system
Quality of Life
Observational study
Female
business
Tomography, X-Ray Computed
Body mass index
Subjects
Details
- ISSN :
- 15323064
- Volume :
- 145
- Database :
- OpenAIRE
- Journal :
- Respiratory medicine
- Accession number :
- edsair.doi.dedup.....645506eeaf4b3a82077f717648d401a9