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Additional file 5 of Microbiota restoration reduces antibiotic-resistant bacteria gut colonization in patients with recurrent Clostridioides difficile infection from the open-label PUNCH CD study

Authors :
Langdon, Amy
Schwartz, Drew J.
Bulow, Christopher
Xiaoqing Sun
Hink, Tiffany
Reske, Kimberly A.
Jones, Courtney
Carey-Ann D. Burnham
Dubberke, Erik R.
Dantas, Gautam
Publication Year :
2021
Publisher :
figshare, 2021.

Abstract

Additional file 5 Fig. S8. Relative abundance of ASVs corresponding to A) Enterobacter, B) Escherichia, C) Citrobacter, and D) Enterococcus tracked temporally after second dose of RBX2660 in the RI group. Fig. S9. Patient origin ARGs over time after A) first RBX2660 and B) second RBX2660 in the RI group. All comparisons non-significant as determined by pairwise Wilcoxon with Benjamini Hochberg correction. n = 17 total patients with A) 27 and B) 45 samples. Fig. S10. Abundance of resistance genes in each metagenomic sample compared to their DFD for resistance genes that were not detected in patients’ day 0 samples or in the donors. For these genes, their abundance and the distance from donor are uncorrelated.

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....6430783cedb961134bc7c06521b9f26a
Full Text :
https://doi.org/10.6084/m9.figshare.14052702.v1