Back to Search Start Over

Draft genome sequences of Helicobacter pylori isolates from Malaysia, cultured from patients with functional dyspepsia and gastric cancer

Authors :
Thevakumar Kavitha
Liang Chung Tay
Halimah Alias
Stephen Rudd
Norzawani Buang M. Yassin
Nadeem O. Kaakoush
HueyTyng Lee
Eng Guan Chua
Nur Siti Khadijah Ramli
Khean-Lee Goh
Joanne Mason
Xinsheng Teh
Mun Fai Loke
Hazel M. Mitchell
Jamuna Vadivelu
S.P. Gunaletchumy
Nur Zafirah Zaidan
Yalda Khosravi
Source :
Journal of bacteriology. 194(20)
Publication Year :
2012

Abstract

Helicobacter pylori is the main bacterial causative agent of gastroduodenal disorders and a risk factor for gastric adenocarcinoma and mucosa-associated lymphoid tissue (MALT) lymphoma. The draft genomes of 10 closely related H. pylori isolates from the multiracial Malaysian population will provide an insight into the genetic diversity of isolates in Southeast Asia. These isolates were cultured from gastric biopsy samples from patients with functional dyspepsia and gastric cancer. The availability of this genomic information will provide an opportunity for examining the evolution and population structure of H. pylori isolates from Southeast Asia, where the East meets the West.

Details

ISSN :
10985530
Volume :
194
Issue :
20
Database :
OpenAIRE
Journal :
Journal of bacteriology
Accession number :
edsair.doi.dedup.....642cd94197836fd0581c22cb9feda85b