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Distribution of caveolin in the muscle spindles of human skeletal muscle
- Source :
- Journal of Anatomy. 224:681-687
- Publication Year :
- 2014
- Publisher :
- Wiley, 2014.
-
Abstract
- The aim of the present study was to demonstrate the location of the different members of the caveolin (cav) family in human muscle spindles. Twenty spindles of three human muscles (vastus medialis, ischiocavernosus, bulbospongiosus) from 12 cadavers were immunohistochemically stained for cav-1, cav-2, and cav-3, and the equatorial and polar regions evaluated. All layers of the outer and inner spindle capsule and all blood vessels within the spindle stained for cav-1 and cav-2. In the muscle spindle, intrafusal muscle fibres stained selectively for cav-3, but with a patchy appearance. Caveolinopathies may therefore also include changes in muscle spindle function.
- Subjects :
- Male
Pathology
medicine.medical_specialty
Histology
Vastus medialis
Muscle spindle
Ischiocavernosus
Biology
Caveolins
Cadaver
medicine
Humans
Muscle, Skeletal
Muscle Spindles
Molecular Biology
Ecology, Evolution, Behavior and Systematics
Aged
Aged, 80 and over
Bulbospongiosus
Skeletal muscle
Original Articles
Cell Biology
Anatomy
Immunohistochemistry
Caveolin 3
Caveolin 2
medicine.anatomical_structure
Caveolin 1
cardiovascular system
Female
Developmental Biology
Subjects
Details
- ISSN :
- 00218782
- Volume :
- 224
- Database :
- OpenAIRE
- Journal :
- Journal of Anatomy
- Accession number :
- edsair.doi.dedup.....6414e02fd630aa1db3e84477355d539e