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A copper-catalyzed three-component reaction of dithioacetals with diazo ketones and ketimines
- Source :
- Organicbiomolecular chemistry. 20(42)
- Publication Year :
- 2022
-
Abstract
- A copper-catalyzed three-component reaction of dithioacetals with diazo-ketones and ketimines has been reported. This reaction proceedsivia/itrapping of the highly active sulfur ylide species, which are generated from thioacetal and carbene intermediates, with isatin-derived ketimine, providing an efficient protocol for the synthesis of acyclic thioacetal derivatives and medium-sized sulfur-containing heterocycles in good to high yields under mild reaction conditions with a broad substrate scope.
Details
- ISSN :
- 14770539
- Volume :
- 20
- Issue :
- 42
- Database :
- OpenAIRE
- Journal :
- Organicbiomolecular chemistry
- Accession number :
- edsair.doi.dedup.....63f81bbc12a4fb66673c1cceff7ecb72