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Figure S2 from Resistance to Pyrrolobenzodiazepine Dimers Is Associated with SLFN11 Downregulation and Can Be Reversed through Inhibition of ATR

Authors :
Jay Harper
Mark Cobbold
David A. Tice
Philip W. Howard
Ronald Herbst
Herren Wu
Changshou Gao
Luke A. Masterson
Kimberly Cook
Kathryn Pugh
Susan Wilson
Nazzareno Dimasi
Jens-Oliver Koopmann
Sonja Hess
Ryan Fleming
Sandrina Phipps
Allison M. Barrett
Hong Chen
Andrew Garcia
Gina D’Angelo
Wen Yu
Raghothama Chaerkady
Shenlan Mao
Publication Year :
2023
Publisher :
American Association for Cancer Research (AACR), 2023.

Abstract

The addition of the ATR inhibitor, AZD6738, did not show synergistic cytotoxicity with SG3199 or ADCs in parental MDA-MB-361 cells

Details

Database :
OpenAIRE
Accession number :
edsair.doi.dedup.....63d95af0ffa8c167232f6d1a26846154
Full Text :
https://doi.org/10.1158/1535-7163.22521297.v1