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Pregabalin-induced first degree atrioventricular block in a young patient treated for pain from extrapulmonary tuberculosis
- Source :
- Monaldi Archives for Chest Disease, Vol 87, Iss 3 (2017)
- Publication Year :
- 2017
-
Abstract
- Pregabalin, widely used in the treatment of several pain disorders, is usually well tolerated. Uncommonly, the drug may induce cardiac side effects, rarely prolongation of the PR interval. The latter has never been described in patients with healthy heart or normal renal function. We characterize a unique case of a young man with extrapulmonary tuberculosis and no detectable or known cardiac or kidney diseases, treated with pregabalin to control the severe pain due to the involvement of the spinal cord by the tuberculosis, showing an atrioventricular (AV) block due to pregabalin administration. The reported case emphasizes the need of monitoring PR interval during treatment with pregabalin, even in patients without background of cardiac or renal diseases.
- Subjects :
- Drug
Pulmonary and Respiratory Medicine
Male
Cardiovascular side effect
Tuberculosis
Tuberculosi
media_common.quotation_subject
Pregabalin
lcsh:Medicine
Pain
Electrocardiography
Young Adult
medicine
Humans
PR interval
Atrioventricular Block
media_common
Kidney
business.industry
lcsh:R
pain
Tuberculosis, Central Nervous System
Spinal cord
medicine.disease
Calcium Channel Blockers
medicine.anatomical_structure
Treatment Outcome
tuberculosis
First-degree atrioventricular block
Anesthesia
cardiovascular side effects
business
Cardiology and Cardiovascular Medicine
Atrioventricular block
medicine.drug
Subjects
Details
- ISSN :
- 11220643
- Volume :
- 87
- Issue :
- 3
- Database :
- OpenAIRE
- Journal :
- Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace
- Accession number :
- edsair.doi.dedup.....63c31344827e64ac0591a2aecb3615eb