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Correlation of specific genetic aberrations and signaling pathways with T-cell inflamed phenotype (TCIP) in head and neck cancer and as novel candidate biomarkers for checkpoint blockade therapy
- Source :
- ResearcherID
- Publication Year :
- 2015
- Publisher :
- American Society of Clinical Oncology (ASCO), 2015.
-
Abstract
- 6079 Background: Anti-PD-1/PD-L1 blockade is active in patients (pts) with head and neck squamous cell carcinoma (HNSCC) (Seiwert ASCO 2014). The T-cell inflamed phenotype (TCIP)/INF-g driven gene ...
- Subjects :
- Cancer Research
business.industry
T cell
Head and neck cancer
Gene deletion
medicine.disease
Phenotype
Head and neck squamous-cell carcinoma
Blockade
stomatognathic diseases
medicine.anatomical_structure
Oncology
Immunology
otorhinolaryngologic diseases
medicine
Cancer research
Signal transduction
business
Gene
Subjects
Details
- ISSN :
- 15277755 and 0732183X
- Volume :
- 33
- Database :
- OpenAIRE
- Journal :
- Journal of Clinical Oncology
- Accession number :
- edsair.doi.dedup.....63afc6598ddcc615c10c0e39966d256e
- Full Text :
- https://doi.org/10.1200/jco.2015.33.15_suppl.6079