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Data of methylome and transcriptome derived from human dilated cardiomyopathy
- Source :
- Data in Brief, Vol 9, Iss C, Pp 382-387 (2016), Data in Brief
- Publication Year :
- 2016
- Publisher :
- Elsevier BV, 2016.
-
Abstract
- Alterations in DNA methylation and gene expression have been implicated in the development of human dilated cardiomyopathy (DCM). Differentially methylated probes (DMPs) and differentially expressed genes (DEGs) were identified between the left ventricle (LV, a pathological locus for DCM) and the right ventricle (RV, a proxy for normal hearts). The data in this DiB are for supporting our report entitled “Methylome analysis reveals alterations in DNA methylation in the regulatory regions of left ventricle development genes in human dilated cardiomyopathy” (Bong-Seok Jo, In-Uk Koh, Jae-Bum Bae, Ho-Yeong Yu, Eun-Seok Jeon, Hae-Young Lee, Jae-Joong Kim, Murim Choi, Sun Shim Choi, 2016) [1].
- Subjects :
- 0301 basic medicine
Locus (genetics)
030204 cardiovascular system & hematology
Biology
lcsh:Computer applications to medicine. Medical informatics
Transcriptome
03 medical and health sciences
0302 clinical medicine
Gene expression
medicine
DEG
DMP
lcsh:Science (General)
Gene
Data Article
Genetics
DCM
Multidisciplinary
Dilated cardiomyopathy
medicine.disease
Molecular biology
030104 developmental biology
medicine.anatomical_structure
Ventricle
Regulatory sequence
DNA methylation
lcsh:R858-859.7
Methylome
lcsh:Q1-390
Subjects
Details
- ISSN :
- 23523409
- Volume :
- 9
- Database :
- OpenAIRE
- Journal :
- Data in Brief
- Accession number :
- edsair.doi.dedup.....6365cd95f02f1e477b4e27ed9e2c292a
- Full Text :
- https://doi.org/10.1016/j.dib.2016.09.006